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Lisse Skincare Serum is an anti-aging skincare treatment designed to brighten complexion and reduce the appearance of fine lines and wrinkles. Marketing campaigns claim that the serum is effective at erasing age spots and dark circles and filling in fine lines and deep wrinkles.
Lisse Serum is only available online. Many sites offer a free trial of the serum, but the details of this trial are unavailable.
Manufacturer information

Little information is available about the manufacturer of Lisse Skincare Serum. Several websites appear to be the authority on the serum, but all of them provide links to a free trial ad which frequently re-directs to another product.
Working process
Like most anti-aging skincare serums, Lisse works as both a moisturizer and a stimulant of collagen and elastin production.
The skin is made up of 60% water. Water is responsible for keeping cells healthy and the skin plump. As the skin ages, it loses its ability to retain water. Dehydrated skin sags and is prone to blemishes.
Collagen and elastin are the two main components of the skin’s underlying structural support matrix. However, as the skin ages, collagen and production slack and degradation increases. Wrinkles and fine lines result.
Unlike other skincare serums, Lisse uses a special system to deliver its active ingredients deep into the skin. Biofil spheres, made of wheat protein, penetrate to the deepest layer of the skin, where they dissolve to release their contents.
Ingredients
Different marketing sites list different ingredients in Lisse’s formula, so it’s difficult to know for sure what the serum contains. Some of the ingredients mentioned are:
Vitamin E is a natural moisturizer and antioxidant, able to quench the free radicals that breakdown the skin’s support matrix.
Cyclomethicone is a synthetic compound added to give lotions a smooth texture and leave the skin feeling soft.
Glycerin is a natural substance that is found in high levels in young skin. It promotes water retention.
Butylene glycol is an alcohol-based substance used to thin creams and make them easy to spread.
Methylparaben is a preservative, which has been implicated as an allergen and a mutagen.
Hydrolyzed wheat protein coats the outside of the biofil spheres, which allow for deep skin penetration.
Ethylhexyl palmitate is a derivative of palm oil, which is used to texturize creams, but has been implicated as an irritant in many creams.
Hydrogenated styrene makes creams cohesive.
Apricot kernel oil is a natural extract with antioxidant, anti-inflammatory, and anti-bacterial properties. It can reduce breakouts and blemishes and slow down the degradation of the collagen matrix.
Advantages
- 30 day free trial
- biofil sphere technology allows for deep penetration of skin
Disadvantages
- Most of the ingredients are more related to texturing the cream than affecting the skin
- Some ingredients are implicated as allergens or irritants
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